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AURKC Antibody: Biotin (ARP53573_P050-Biotin)

Product Specifications

Gene Name

Aurora kinase C

Gene Aliases

AIE2, AIK3, ARK3, AurC, SPGF5, STK13, HEL-S-90, aurora-C

Gene ID

6795

Swiss Prot

Q9UQB9

Accession Number

NP_001015878

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence PRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGK

Target

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Partner Proteins

SRPK1; AURKB; HIST1H3A; INCENP; BIRC5; TACC2; UBC; HSP90AA1; BRCA1; LNX1; NEDD4L; NEDD4; CENPA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36 kDa

Shipping Conditions

Wet Ice

Protein Length

309

NCBI Gene Symbol

AURKC

Protein Name

Aurora kinase C

Nucleotide Accession Number

NM_001015878

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