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ASB7 Antibody - middle region : Biotin (ARP53463_P050-Biotin)

Selected Variant

ARP53463_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Ankyrin repeat and SOCS box containing 7

Gene Aliases

FLJ22551

Gene ID

140460

Swiss Prot

Q9H672

Accession Number

NP_937886

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ASB7

Target

The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.

Partner Proteins

HMBOX1; CCDC136; HIF1AN; ASB4; GANAB; CCT7; RNF7; CUL5; VCL; TCEB2; TCEB1; FGG; FGB; FGA; ATF4; UBD; SRRM1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

Shipping Conditions

Wet Ice

Protein Length

318

NCBI Gene Symbol

ASB7

NCBI GB Accession Number

ASB7

Host or Source

Rabbit

Protein Name

Ankyrin repeat and SOCS box protein 7

Nucleotide Accession Number

NM_198243

Peptide Sequence

QTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPC

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