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EIF5 Antibody - N-terminal region : Biotin (ARP53443_P050-Biotin)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 5

Gene Aliases

EIF-5, EIF-5A

Gene ID

1983

Swiss Prot

P55010

Accession Number

NP_892116

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF5

Target

EIF5 catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]) .

Partner Proteins

DUSP12; HUWE1; UBC; TUBB; UBFD1; SCLY; ISOC1; MAT2B; FERMT2; YWHAQ; STK24; YWHAZ; YWHAH; YWHAE; EIF4H; VCL; SNRPD1; PCYT2; PFAS; PDHB; PAFAH1B1; HSPA9; HNRNPK; GNAI3; GLA; G6PD; DFFA; TBCB; CAPNS1; ALDH7A1; LMNA; PUM1; NRGN; FN1; EIF3B; RPL29; APP; Nedd4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that EIF5 is expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

49kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

431

NCBI Gene Symbol

EIF5

NCBI GB Accession Number

EIF5

Host or Source

Rabbit

Protein Name

Eukaryotic translation initiation factor 5

Nucleotide Accession Number

NM_183004

Peptide Sequence

SVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPT

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