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GEFT Antibody - C-terminal region : FITC (ARP53438_P050-FITC)

Selected Variant

ARP53438_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Rho guanine nucleotide exchange factor (GEF) 25

Gene Aliases

GEFT, p63RhoGEF

Gene ID

115557

Swiss Prot

Q86VW2

Accession Number

NP_891992

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GEFT

Target

The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]) .[supplied by OMIM].

Partner Proteins

PRKCG; RAC1; RHOA; CDC42

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 85%; Guinea Pig: 85%; Horse: 85%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 85%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

References & Citations

Lutz, S., (2007) Science 318 (5858), 1923-1927

Shipping Conditions

Wet Ice

Protein Length

580

NCBI Gene Symbol

ARHGEF25

NCBI GB Accession Number

ARHGEF25

Host or Source

Rabbit

Protein Name

Rho guanine nucleotide exchange factor 25

Nucleotide Accession Number

NM_182947

Peptide Sequence

RLGDQAQGSTHTPINGSLPSLLLSPKGEVARALLPLDKQALGDIPQAPHD

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