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GEFT Antibody - C-terminal region : FITC (ARP53438_P050-FITC)

Product Specifications

Gene Name

Rho guanine nucleotide exchange factor (GEF) 25

Gene Aliases

GEFT, p63RhoGEF

Gene ID

115557

Swiss Prot

Q86VW2

Accession Number

NP_891992

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GEFT

Target

The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]) .[supplied by OMIM].

Partner Proteins

PRKCG; RAC1; RHOA; CDC42

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 85%; Guinea Pig: 85%; Horse: 85%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 85%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

References & Citations

Lutz, S., (2007) Science 318 (5858), 1923-1927

Shipping Conditions

Wet Ice

Product Datasheet

Anti-ARHGEF25 (ARP53438_P050-FITC) antibody

Protein Length

580

NCBI Gene Symbol

ARHGEF25

NCBI GB Accession Number

ARHGEF25

Host or Source

Rabbit

Protein Name

Rho guanine nucleotide exchange factor 25

Nucleotide Accession Number

NM_182947

Peptide Sequence

RLGDQAQGSTHTPINGSLPSLLLSPKGEVARALLPLDKQALGDIPQAPHD

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