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CCDC50 Antibody - middle region : HRP (ARP53355_P050-HRP)

Product Specifications

Gene Name

Coiled-coil domain containing 50

Gene Aliases

YMER, C3orf6, DFNA44

Gene ID

152137

Swiss Prot

Q8IVM0

Accession Number

NP_848018

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CCDC50

Target

CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF) -mediated cell signaling.

Partner Proteins

UBC; SH3RF2; RIPK1; TNFAIP3; EGFR; RPS3A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Bohgaki, M., (2008) Biochim. Biophys. Acta 1783 (5), 826-837

Shipping Conditions

Wet Ice

Protein Length

482

NCBI Gene Symbol

CCDC50

NCBI GB Accession Number

CCDC50

Host or Source

Rabbit

Protein Name

Coiled-coil domain-containing protein 50

Nucleotide Accession Number

NM_178335

Peptide Sequence

GMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQV

Frequently Asked Questions

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