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KLC3 Antibody - middle region : FITC (ARP53346_P050-FITC)

Product Specifications

Gene Name

Kinesin light chain 3

Gene Aliases

KLC2, KLCt, KLC2L, KNS2B

Gene ID

147700

Swiss Prot

Q6P597

Accession Number

NP_803136

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human KLC3

Target

KLC3 is a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.

Partner Proteins

CENPP; CCDC36; CEP57L1; SPERT; KLC3; ZNF417; CCDC64B; ZNF572; BBS5; SNAP47; DTX2; USHBP1; IMP3; NECAB2; MBIP; WAC; ABI3; KDM1A; NDC80; PDE4DIP; STX11; TSNAX; TCF4; VPS52; QARS; KRT15; KRT13; GEM; CCNH; YWHAE; DYNC1I1; CUL2; CROCC; KIF5A; KIF5B; YWHAG; YWH

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 77%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

55kDa

References & Citations

Zhang, Y., (2004) Dev. Biol. 275 (1), 23-33

Shipping Conditions

Wet Ice

Protein Length

504

NCBI Gene Symbol

KLC3

NCBI GB Accession Number

KLC3

Host or Source

Rabbit

Protein Name

Kinesin light chain 3

Nucleotide Accession Number

NM_177417

Peptide Sequence

LLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNK

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