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ZCCHC12 Antibody - N-terminal region : HRP (ARP53282_P050-HRP)

Product Specifications

Gene Name

Zinc finger, CCHC domain containing 12

Gene Aliases

SIZN, SIZN1, PNMA7A

Gene ID

170261

Swiss Prot

Q6PEW1

Accession Number

NP_776159

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ZCCHC12

Target

ZCCHC12 contains 1 CCHC-type zinc finger. ZCCHC12 is the transcriptional coactivator in the bone morphogenetic protein (BMP) -signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.

Partner Proteins

PNMA1; SUMO1; TFCP2; MAGEA11; SUMO2; APP; SMAD1; CREBBP; UBC; APPBP2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Cho, G., (2008) Mol. Cell. Biol. 28 (5), 1565-1572

Shipping Conditions

Wet Ice

Product Datasheet

Anti-ZCCHC12 (ARP53282_P050-HRP) antibody

Protein Length

402

NCBI Gene Symbol

ZCCHC12

NCBI GB Accession Number

ZCCHC12

Host or Source

Rabbit

Protein Name

Zinc finger CCHC domain-containing protein 12

Nucleotide Accession Number

NM_173798

Peptide Sequence

AREVMRVLQATNPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQAQGE

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