TTL Antibody - middle region : HRP (ARP53199_P050-HRP)
Product Specifications
Gene Name
Tubulin tyrosine ligase
Gene Aliases
MGC46235
Gene ID
150465
Swiss Prot
Q8NG68
Accession Number
NP_714923
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TTL
Target
TTL catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529) . Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]) .[supplied by OMIM].
Partner Proteins
ELAVL1
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
43kDa
References & Citations
Erck, C., (2003) Cytogenet. Genome Res. 101 (1), 47-53
Shipping Conditions
Wet Ice
Protein Length
377
NCBI Gene Symbol
TTL
NCBI GB Accession Number
TTL
Host or Source
Rabbit
Protein Name
Tubulin--tyrosine ligase
Nucleotide Accession Number
NM_153712
Peptide Sequence
LYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFF
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