KHDRBS2 Antibody - N-terminal region: FITC (ARP53109_P050-FITC)
Product Specifications
Gene Name
KH domain containing, RNA binding, signal transduction associated 2
Gene Aliases
SLM1, SLM-1
Gene ID
202559
Swiss Prot
Q5VWX1
Accession Number
NP_689901
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS2
Target
KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly (A) and poly (U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
Partner Proteins
HBZ; DOCK2; CIRBP; TYMSOS; LINC01018; KHDRBS2; ZFC3H1; CATSPER1; YTHDC1; PRR3; NABP1; AEN; NCOA5; NPDC1; RBMX; PRPF31; CHTOP; HNRNPR; MTA1; TYK2; SULT1A3; SPG7; SDCBP; RBM3; PTK6; UBC; KHDRBS3; HNRNPK; LYN; HNRNPC; HNRNPA2B1; HNRNPA1; FGG; FGB; FGA; DSG1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
39kDa
Shipping Conditions
Wet Ice
Protein Length
349
NCBI Gene Symbol
KHDRBS2
Protein Name
KH domain-containing, RNA-binding, signal transduction-associated protein 2
Nucleotide Accession Number
NM_152688
Curated Selection
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