EME1 Antibody - N-terminal region : Biotin (ARP52987_P050-Biotin)
Product Specifications
Gene Name
Essential meiotic endonuclease 1 homolog 1 (S. pombe)
Gene Aliases
MMS4L, SLX2A
Gene ID
146956
Swiss Prot
Q96AY2
Accession Number
NP_689676
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human EME1
Target
EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]) .[supplied by OMIM].
Partner Proteins
Vpr; MUS81; APP; SLX1A; EME1; SLX4; SUMO2; SLX1B
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 85%; Dog: 93%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
63kDa
References & Citations
Taylor, E.R. (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (10), 3757-3762
Shipping Conditions
Wet Ice
Protein Length
570
NCBI Gene Symbol
EME1
NCBI GB Accession Number
EME1
Host or Source
Rabbit
Protein Name
Crossover junction endonuclease EME1
Nucleotide Accession Number
NM_152463
Peptide Sequence
MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDIS
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