FBXL14 Antibody - N-terminal region : Biotin (ARP52968_P050-Biotin)
Product Specifications
Gene Name
F-box and leucine-rich repeat protein 14
Gene Aliases
Fbl14
Gene ID
144699
Swiss Prot
Q8N1E6
Accession Number
NP_689654
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL14
Target
FBXL14 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein) -type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM].
Partner Proteins
DICER1; HSP90AA1; COPS5; COPS6; CUL1; Snai1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
46kDa
References & Citations
Jin, J., (2004) Genes Dev. 18 (21), 2573-2580
Shipping Conditions
Wet Ice
Protein Length
418
NCBI Gene Symbol
FBXL14
NCBI GB Accession Number
FBXL14
Host or Source
Rabbit
Protein Name
F-box/LRR-repeat protein 14
Nucleotide Accession Number
NM_152441
Peptide Sequence
WRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGIRRVQILSLRRSLSY
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