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GRPEL2 Antibody - middle region : HRP (ARP52949_P050-HRP)

Product Specifications

Gene Name

GrpE-like 2, mitochondrial (E. coli)

Gene Aliases

Mt-GrpE#2

Gene ID

134266

Swiss Prot

Q8TAA5

Accession Number

NP_689620

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GRPEL2

Target

GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.

Partner Proteins

ELAVL1; UBC; HSPA4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

References & Citations

Naylor, D.J., (1998) J. Biol. Chem. 273 (33), 21169-21177

Shipping Conditions

Wet Ice

Product Datasheet

Anti-GRPEL2 (ARP52949_P050-HRP) antibody

Protein Length

225

NCBI Gene Symbol

GRPEL2

NCBI GB Accession Number

GRPEL2

Host or Source

Rabbit

Protein Name

GrpE protein homolog 2, mitochondrial

Nucleotide Accession Number

NM_152407

Peptide Sequence

HEHELICHVPAGVGVQPGTVALVRQDGYKLHGRTIRLARVEVAVESQRRL

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