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HUS1B Antibody - N-terminal region : Biotin (ARP52871_P050-Biotin)

Product Specifications

Gene Name

HUS1 checkpoint homolog b (S. pombe)

Gene Aliases

MGC126746, MGC126748, RP11-532F6.1

Gene ID

135458

Swiss Prot

Q8NHY5

Accession Number

NP_683762

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HUS1B

Target

HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

Partner Proteins

RAD9B; RAD9A; HUS1; RAD1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

References & Citations

Dufault, V.M., (2003) Genomics 82 (6), 644-651

Shipping Conditions

Wet Ice

Protein Length

278

NCBI Gene Symbol

HUS1B

NCBI GB Accession Number

HUS1B

Host or Source

Rabbit

Protein Name

Checkpoint protein HUS1B

Nucleotide Accession Number

NM_148959

Peptide Sequence

ELFIHVSGTVARLAKVCVLRVRPDSLCFGPAGSGGLHEARLWCEVRQGAF

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