ACVR1C Antibody - N-terminal region : FITC (ARP52836_P050-FITC)
Product Specifications
Gene Name
Activin A receptor, type IC
Gene Aliases
ALK7, ACVRLK7
Gene ID
130399
Swiss Prot
Q8NER5
Accession Number
NP_660302
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1C
Target
ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]) .[supplied by OMIM].
Partner Proteins
HSP90AA1; TDGF1; INHBB
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 83%; Guinea Pig: 80%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 81%; Rabbit: 100%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
55kDa
References & Citations
Andersson, O., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (20), 7252-7256
Shipping Conditions
Wet Ice
Protein Length
493
NCBI Gene Symbol
ACVR1C
NCBI GB Accession Number
ACVR1C
Host or Source
Rabbit
Protein Name
Activin receptor type-1C
Nucleotide Accession Number
NM_145259
Peptide Sequence
QVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVP
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