DEDD2 Antibody - middle region: FITC (ARP52558_P050-FITC)
Product Specifications
Gene Name
Death effector domain containing 2
Gene Aliases
FLAME3, FLAME-3
Gene ID
162989
Swiss Prot
Q8WXF8
Accession Number
NP_579874
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DEDD2
Target
DEDD2 may play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. DEDD2 may regulate degradation of intermediate filaments during apoptosis. DEDD2 may play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
Partner Proteins
CDCA7L; ATG16L1; CDK6; RBFOX2; NR2E3; HNRNPAB; RHOXF2; GTF3C3; DEDD2; DEDD; CFLAR; CASP8; CASP10
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
36
Shipping Conditions
Wet Ice
Protein Length
326
NCBI Gene Symbol
DEDD2
Protein Name
DNA-binding death effector domain-containing protein 2
Nucleotide Accession Number
NM_133328
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