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ASB12 Antibody - C-terminal region : Biotin (ARP52534_P050-Biotin)

Product Specifications

Gene Name

Ankyrin repeat and SOCS box containing 12

Gene Aliases

FLJ39577

Gene ID

142689

Swiss Prot

Q8WXK4

Accession Number

NP_569059

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ASB12

Target

ASB12 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The SOCS box domain has not yet been annotated for the protein. The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The SOCS box domain has not yet been annotated for this encoded protein.

Partner Proteins

ACTB; DHX36; CADPS2; SRRT; MTHFD1L; NUDT21; RBM6; DHX38; PRDX6; AIFM1; RBM10; RCN2; PFN2; PFN1; PFKFB3; MYH10; KRT8; GLO1; FGG; CKB; TUFM; TCEB2; TCEB1; SFPQ; RPL38; LZTR1; RNF7; CUL5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Ross, M.T., (2005) Nature 434 (7031), 325-337

Shipping Conditions

Wet Ice

Protein Length

309

NCBI Gene Symbol

ASB12

NCBI GB Accession Number

ASB12

Host or Source

Rabbit

Protein Name

Ankyrin repeat and SOCS box protein 12

Nucleotide Accession Number

NM_130388

Peptide Sequence

DDKGIALLLQARATPRSLLSQVRLVVRRALCQAGQPQAINQLDIPPMLIS

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