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DNAJB6 Antibody - N-terminal region : HRP (ARP52499_P050-HRP)

Selected Variant

ARP52499_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

DnaJ (Hsp40) homolog, subfamily B, member 6

Gene Aliases

DJ4, MRJ, DnaJ, HSJ2, HHDJ1, HSJ-2, MSJ-1, LGMD1D, LGMD1E, LGMDD1

Gene ID

10049

Swiss Prot

O75190

Accession Number

NP_490647

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DNAJB6

Target

DNAJB6 is a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons.This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.

Partner Proteins

UBC; FAM96A; FAM96B; STIP1; STUB1; BAG2; BAG3; BAG4; MLF2; HSPA8; FKBP5; BAG1; TARDBP; SOX2; HDAC11; POLR1D; APP; BRMS1; CUL2; CUL3; EBNA-LP; PIK3CA; MYC; ALKBH1; HDAC4; TP63; TP73; TP53; SIRT2; HDAC6; USP8; KRT18

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 83%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Meccariello, R., (2008) Gen. Comp. Endocrinol. 156 (1), 91-103

Shipping Conditions

Wet Ice

Protein Length

326

NCBI Gene Symbol

DNAJB6

NCBI GB Accession Number

DNAJB6

Host or Source

Rabbit

Protein Name

DnaJ homolog subfamily B member 6

Nucleotide Accession Number

NM_058246

Peptide Sequence

PENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGSHFDS

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