MED8 Antibody - N-terminal region : FITC (ARP52440_P050-FITC)
Product Specifications
Gene Name
Mediator complex subunit 8
Gene Aliases
ARC32
Gene ID
112950
Swiss Prot
Q96G25-2
Accession Number
NP_443109
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MED8
Target
MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase.This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.
Partner Proteins
PNMA1; KRT40; CDK19; CDK8; MED19; MED26; FBXW7; EPAS1; MED29; MED18; CPSF1; MED4; MED16; MED12; MED24; MED21; MED14; MED1; HIST1H1E; APP; MED11; SUMO2; MED10; RBX1; CTDP1; CUL2; TCEB2; TCEB1; MED28; OBFC1; ZC3H13; TRIP4; TADA2A; THOC7; PHYHIP; MED20; MED9
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
33kDa
References & Citations
Leonard, V.H., (2006) J. Virol. 80 (19), 9667-9675
Shipping Conditions
Wet Ice
Protein Length
301
NCBI Gene Symbol
MED8
NCBI GB Accession Number
MED8
Host or Source
Rabbit
Protein Name
Mediator of RNA polymerase II transcription subunit 8
Nucleotide Accession Number
NM_052877
Peptide Sequence
MQREEKQLEASLDALLSQVADLKNSLGSFICKLENEYGRLTWPSVLDSFA
Subunit
8
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