MED8 Antibody - N-terminal region : Biotin (ARP52440_P050-Biotin)

Product Specifications

Gene Name

Mediator complex subunit 8

Gene Aliases

ARC32

Gene ID

112950

Swiss Prot

Q96G25-2

Accession Number

NP_443109

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MED8

Target

MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase.This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.

Partner Proteins

PNMA1; KRT40; CDK19; CDK8; MED19; MED26; FBXW7; EPAS1; MED29; MED18; CPSF1; MED4; MED16; MED12; MED24; MED21; MED14; MED1; HIST1H1E; APP; MED11; SUMO2; MED10; RBX1; CTDP1; CUL2; TCEB2; TCEB1; MED28; OBFC1; ZC3H13; TRIP4; TADA2A; THOC7; PHYHIP; MED20; MED9

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.