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COL4A3BP Antibody - N-terminal region : Biotin (ARP52418_P050-Biotin)

Product Specifications

Gene Name

Collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

Gene Aliases

CERT, GPBP, CERTL, MRD34, STARD11, COL4A3BP

Gene ID

10087

Swiss Prot

Q9Y5P4

Accession Number

NP_112729

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human COL4A3BP

Target

COL4A3BP is a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport.This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Two transcripts exist for this gene.

Partner Proteins

ACTL8; ITGB3BP; ARL6IP1; COL4A3BP; CSNK1G2; UBC; NAP1L5; PACSIN2; PNMA2; PPP2R5C; FTL; TGM2; CBS; MARK2; RTN3; POM121; RTN4; COL4A3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

68kDa

References & Citations

Saito, S., (2008) J. Biol. Chem. 283 (10), 6584-6593

Shipping Conditions

Wet Ice

Protein Length

598

NCBI Gene Symbol

COL4A3BP

NCBI GB Accession Number

COL4A3BP

Host or Source

Rabbit

Protein Name

Collagen type IV alpha-3-binding protein

Nucleotide Accession Number

NM_031361

Peptide Sequence

PPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICL

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