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CRY2 Antibody - N-terminal region : FITC (ARP52398_P050-FITC)

Selected Variant

ARP52398_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Cryptochrome 2 (photolyase-like)

Gene Aliases

HCRY2, PHLL2

Gene ID

1408

Swiss Prot

Q49AN0

Accession Number

NP_066940

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CRY2

Target

CRY2 is a blue light-dependent regulator of the circadian feedback loop.CRY2 inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. CRY2 acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity.CRY2 has no photolyase activity. CRY2 is capable of translocating circadian clock core proteins such as PER proteins to the nucleus.CRY2 may inhibit CLOCK NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.

Partner Proteins

MTUS2; PDE9A; CTBP1; UBC; FBXL3; FBXL21; BTRC; CUL1; SKP1; ATXN1; Csnk1e; PER3; PER2; PER1; PPP5C; TTC1; CRY2; TIMELESS

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

Shipping Conditions

Wet Ice

Protein Length

593

NCBI Gene Symbol

CRY2

NCBI GB Accession Number

CRY2

Host or Source

Rabbit

Protein Name

Cryptochrome-2

Nucleotide Accession Number

NM_021117

Peptide Sequence

IELNGQKPPLTYKRFQAIISRMELPKKPVGLVTSQQMESCRAEIQENHDE

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