COPB1 Antibody - middle region : FITC (ARP52371_P050-FITC)

Product Specifications

Gene Name

Coatomer protein complex, subunit beta 1

Gene Aliases

COPB, BARMACS

Gene ID

1315

Swiss Prot

P53618

Accession Number

NP_057535

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human COPB1

Target

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Partner Proteins

SUMO2; NUDCD1; UBC; RNF2; EZH2; KLC1; DIAPH1; ARCN1; ACACA; COPG1; COPZ1; TLE3; FBXO6; UBD; KCNK3; KCNK9; NPM1; HDAC10; ERBB2IP; SNTA1; LZTS2; VPS18; NUB1; SERTAD1; FOXB1; IRAK3; TANK; ID1; HLA-DPB1; GRB2; XRCC6; FN1; CFTR; FMNL1; COPG2; COPE; COPB2; COPA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.