COPB1 Antibody - middle region : Biotin (ARP52371_P050-Biotin)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

SUMO2; NUDCD1; UBC; RNF2; EZH2; KLC1; DIAPH1; ARCN1; ACACA; COPG1; COPZ1; TLE3; FBXO6; UBD; KCNK3; KCNK9; NPM1; HDAC10; ERBB2IP; SNTA1; LZTS2; VPS18; NUB1; SERTAD1; FOXB1; IRAK3; TANK; ID1; HLA-DPB1; GRB2; XRCC6; FN1; CFTR; FMNL1; COPG2; COPE; COPB2; COPA

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.