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SEC23IP Antibody - N-terminal region : HRP (ARP52295_P050-HRP)

Product Specifications

Gene Name

SEC23 interacting protein

Gene Aliases

P125, P125A, MSTP053, iPLA1beta

Gene ID

11196

Swiss Prot

Q9Y6Y8

Accession Number

NP_009121

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SEC23IP

Target

COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway.

Partner Proteins

SSC5D; HSPB11; UBC; WWOX; SEPT11; NUDCD2; ZNF518B; URM1; MTHFSD; TBC1D13; ZNF593; SSU72; DSTN; KYNU; UBE2H; TPM3; TPI1; PRDX2; XIAP; HERC2; TSG101; PCNA; POLD4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SEC23IP is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

111kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-SEC23IP (ARP52295_P050-HRP) antibody

Protein Length

1000

NCBI Gene Symbol

SEC23IP

NCBI GB Accession Number

SEC23IP

Host or Source

Rabbit

Protein Name

SEC23-interacting protein

Nucleotide Accession Number

NM_007190

Peptide Sequence

VPFIPVTQASASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQTFSYFS

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