COPS8 Antibody - middle region: Biotin (ARP52242_P050-Biotin)
Product Specifications
Gene Name
COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
Gene Aliases
COP9, CSN8, SGN8
Gene ID
10920
Swiss Prot
Q99627
Accession Number
NP_006701
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human COPS8
Target
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Partner Proteins
USHBP1; GPS1; cul1; WDR77; SRRT; COPS7A; VIM; COPS4; FBXO6; FBXW4; COPS5; vpr; IRF5; DDIT3; COPS2; COPS3; COPS6; PINK1; RFWD2; CUL4A; UBC; LRR1; DDA1; DDB2; DCUN1D1; VPRBP; CUL2; CUL3; CUL4B; CUL5; NEDD8; JUN; GFER; ERCC8; DDB1; CTNNB1; RAE1; COPS8; EIF3E
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Sample Type
There is BioGPS gene expression data showing that COPS8 is expressed in HepG2
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
23kDa
Shipping Conditions
Wet Ice
Protein Length
209
NCBI Gene Symbol
COPS8
Protein Name
COP9 signalosome complex subunit 8
Nucleotide Accession Number
NM_006710
Curated Selection
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