FRS3 Antibody - middle region : Biotin (ARP52228_P050-Biotin)
Product Specifications
Gene Name
Fibroblast growth factor receptor substrate 3
Gene Aliases
SNT2, FRS2B, SNT-2, FRS2beta, FRS2-beta
Gene ID
10817
Swiss Prot
O43559
Accession Number
NP_006644
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human FRS3
Target
FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
NOTCH2NL; RFX6; SPERT; ADAMTSL4; SH3KBP1; CD2AP; SPRY2; TRIP6; TCF4; PLSCR1; GATA1; ERBB2; CBL; AES; ELAVL1; RND1; KARS; BMPR2; NTRK2; PRKCI; NTRK1; MAPK1; PTPN11; FGFR1; GRB2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
54kDa
References & Citations
Huang, L., (2006) Oncogene 25 (49), 6457-6466
Shipping Conditions
Wet Ice
Protein Length
492
NCBI Gene Symbol
FRS3
NCBI GB Accession Number
FRS3
Host or Source
Rabbit
Protein Name
Fibroblast growth factor receptor substrate 3
Nucleotide Accession Number
NM_006653
Peptide Sequence
GFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC402853-100 1x 100 µL
CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402823-100 1x 100 µL
BMI1 (Oncogene and Stem Cell Marker) (BMI1/2823), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details