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HSPH1 Antibody - middle region : HRP (ARP52217_P050-HRP)

Product Specifications

Gene Name

Heat shock 105kDa/110kDa protein 1

Gene Aliases

HSP105, HSP105A, HSP105B, NY-CO-25

Gene ID

10808

Swiss Prot

Q92598

Accession Number

NP_006635

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HSPH1

Target

HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. It inhibits HSPA8/HSC70 ATPase and chaperone activities.

Partner Proteins

HUWE1; UBC; SUMO2; SUMO3; HSPA8; MDM2; ILK; SET; PPM1G; PLOD2; HSPA4; DPYSL2; CTNNA1; PARVA; PUS7; SAMHD1; XPO7; FAF1; CARM1; SEC23A; PRMT3; FARSB; RANBP3; HIRIP3; HIST1H4A; USP11; SF1; UGP2; HECW2; FBXO6; TARDBP; CFTR; METTL21A; env; NOS2; HSP90AB1; HSP9

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

HSPH1 is strongly supported by BioGPS gene expression data to be expressed in 721_B, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

97kDa

References & Citations

Meares, G.P., (2008) Cell. Signal. 20 (2), 347-358

Shipping Conditions

Wet Ice

Protein Length

858

NCBI Gene Symbol

HSPH1

NCBI GB Accession Number

HSPH1

Host or Source

Rabbit

Protein Name

Heat shock protein 105 kDa

Nucleotide Accession Number

NM_006644

Peptide Sequence

EENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQ

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