GRAP Antibody - middle region: FITC (ARP52210_P050-FITC)
Product Specifications
Gene Name
GRB2-related adaptor protein
Gene Aliases
DFNB114
Gene ID
10750
Swiss Prot
Q13588
Accession Number
NP_006604
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GRAP
Target
This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
Partner Proteins
TRIM21; RBPMS; UBC; ARHGAP32; KHDRBS1; LAT; SHC1; SOS1; PLCG1; KIT; LCK; FYN; FASLG; EPOR; GAB2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
25kDa
Shipping Conditions
Wet Ice
Protein Length
217
NCBI Gene Symbol
GRAP
Protein Name
GRB2-related adapter protein
Nucleotide Accession Number
NM_006613
Curated Selection
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