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APPBP2 Antibody - middle region : Biotin (ARP52171_P050-Biotin)

Product Specifications

Gene Name

Amyloid beta precursor protein (cytoplasmic tail) binding protein 2

Gene Aliases

PAT1, APP-BP2, HS.84084

Gene ID

10513

Swiss Prot

Q92624

Accession Number

NP_006371

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human APPBP2

Target

APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. APPBP2 has been found to be highly expressed in breast cancer.The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.

Partner Proteins

WDR24; RASSF5; RNF34; CTC1; LONRF3; RNF128; SLC25A23; C1orf50; ZNF747; ARMCX5; CCNL1; LANCL2; UGGT2; ANKRD10; UBE2R2; FXYD7; LUC7L2; LUZP4; AK3; ERO1L; ST8SIA5; SNX5; RRS1; TCF25; SYNRG; FSTL1; TBL3; CORO2B; DHRS2; AIM2; KLF11; HIST1H2AK; NPRL3; WAS; TAF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

References & Citations

Benboudjema, L., (2003) J. Virol. 77 (17), 9192-9203

Shipping Conditions

Wet Ice

Protein Length

585

NCBI Gene Symbol

APPBP2

NCBI GB Accession Number

APPBP2

Host or Source

Rabbit

Protein Name

Amyloid protein-binding protein 2

Nucleotide Accession Number

NM_006380

Peptide Sequence

QASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLN

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