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DLC1 Antibody - C-terminal region : HRP (ARP52138_P050-HRP)

Product Specifications

Gene Name

Deleted in liver cancer 1

Gene Aliases

HP, ARHGAP7, STARD12, p122-RhoGAP

Gene ID

10395

Swiss Prot

Q9Y238

Accession Number

EAW63852

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1

Target

This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.

Partner Proteins

DDB1; FBXW5; CUL1; CUL2; CUL3; CUL4A; UBC; TENC1; CAV1; S100A10; WWC1; AKT1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that DLC1 is expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-DLC1 (ARP52138_P050-HRP) antibody

Protein Length

467

NCBI Gene Symbol

DLC1

NCBI GB Accession Number

DLC1

Host or Source

Rabbit

Protein Name

Deleted in lung and esophageal cancer protein 1

Nucleotide Accession Number

NM_001164271

Peptide Sequence

NLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGL

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