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DLC1 Antibody - C-terminal region : FITC (ARP52138_P050-FITC)

Selected Variant

ARP52138_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Deleted in liver cancer 1

Gene Aliases

HP, ARHGAP7, STARD12, p122-RhoGAP

Gene ID

10395

Swiss Prot

Q9Y238

Accession Number

EAW63852

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1

Target

This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.

Partner Proteins

DDB1; FBXW5; CUL1; CUL2; CUL3; CUL4A; UBC; TENC1; CAV1; S100A10; WWC1; AKT1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that DLC1 is expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

Shipping Conditions

Wet Ice

Protein Length

467

NCBI Gene Symbol

DLC1

NCBI GB Accession Number

DLC1

Host or Source

Rabbit

Protein Name

Deleted in lung and esophageal cancer protein 1

Nucleotide Accession Number

NM_001164271

Peptide Sequence

NLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGL

Price

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