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BCKDK Antibody - N-terminal region : Biotin (ARP52131_P050-Biotin)

Product Specifications

Gene Name

Branched chain ketoacid dehydrogenase kinase

Gene Aliases

BDK, BCKDKD

Gene ID

10295

Swiss Prot

O14874

Accession Number

NP_005872

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human BCKDK

Target

BCKDK belongs to the PDK/BCKDK protein kinase family. It contains 1 histidine kinase domain. BCKDK catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. BCKDK is the key enzyme that regulates the activity state of the BCKD complex.

Partner Proteins

UBC; SUMO1; NEDD8; LSM8; STAT3; EPS8; APP; NR5A2; TERF2; TRAF4; FAM98B; CAB39L; RNF219; CAB39; RTCA; BCKDHA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

412

NCBI Gene Symbol

BCKDK

NCBI GB Accession Number

BCKDK

Host or Source

Rabbit

Protein Name

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial

Nucleotide Accession Number

NM_005881

Peptide Sequence

CLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLD

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