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ACTR1B Antibody - middle region : HRP (ARP52098_P050-HRP)

Product Specifications

Gene Name

ARP1 actin-related protein 1 homolog B, centractin beta (yeast)

Gene Aliases

PC3, ARP1B, CTRN2

Gene ID

10120

Swiss Prot

P42025

Accession Number

NP_005726

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ACTR1B

Target

ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.

Partner Proteins

SEH1L; ACTR10; DCTN4; DCTN2; ACTR1A; RABEP1; LMNB1; DCTN3; APP; SMAD6; CUL3; UBC; TK1; MAPK6; CSNK2B; Dctn1; Capza1; CHD3; ACTA1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ACTR1B is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 77%; Zebrafish: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42kDa

Shipping Conditions

Wet Ice

Protein Length

376

NCBI Gene Symbol

ACTR1B

NCBI GB Accession Number

ACTR1B

Host or Source

Rabbit

Protein Name

Beta-centractin

Nucleotide Accession Number

NM_005735

Peptide Sequence

VGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVL

Frequently Asked Questions

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