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SAE1 Antibody - N-terminal region : HRP (ARP52084_P050-HRP)

Product Specifications

Gene Name

SUMO1 activating enzyme subunit 1

Gene Aliases

AOS1, SUA1, UBLE1A, HSPC140

Gene ID

10055

Swiss Prot

Q9UBE0

Accession Number

NP_005491

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1

Target

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]) .

Partner Proteins

FUS; USP39; SUMO2; HSPA2; HSPA1A; UBC; TRMT10A; DPP9; RPRD1B; NPLOC4; OSGEP; PANK4; WDR4; CUL5; TPD52L2; SRP14; RANGAP1; PPP2R5E; MCM3; LPP; DHPS; CALU; ADSL; AARS; PDE12; TP53RK; UBE2I; UBA2; BAG3; PTK2; IL3RA; APP; SUMO1; ETV4; BCL6; UBE2E3; SUMO3; SP10

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SAE1 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

Shipping Conditions

Wet Ice

Protein Length

346

NCBI Gene Symbol

SAE1

NCBI GB Accession Number

SAE1

Host or Source

Rabbit

Protein Name

SUMO-activating enzyme subunit 1

Nucleotide Accession Number

NM_005500

Peptide Sequence

VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE

Frequently Asked Questions

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