SAE1 Antibody - N-terminal region : Biotin (ARP52084_P050-Biotin)

Product Specifications

Gene Name

SUMO1 activating enzyme subunit 1

Gene Aliases

AOS1, SUA1, UBLE1A, HSPC140

Gene ID

10055

Swiss Prot

Q9UBE0

Accession Number

NP_005491

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1

Target

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]) .

Partner Proteins

FUS; USP39; SUMO2; HSPA2; HSPA1A; UBC; TRMT10A; DPP9; RPRD1B; NPLOC4; OSGEP; PANK4; WDR4; CUL5; TPD52L2; SRP14; RANGAP1; PPP2R5E; MCM3; LPP; DHPS; CALU; ADSL; AARS; PDE12; TP53RK; UBE2I; UBA2; BAG3; PTK2; IL3RA; APP; SUMO1; ETV4; BCL6; UBE2E3; SUMO3; SP10

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

SAE1 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.