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DYNC1I1 Antibody - N-terminal region : FITC (ARP52047_P050-FITC)

Product Specifications

Gene Name

Dynein, cytoplasmic 1, intermediate chain 1

Gene Aliases

DNCI1, DNCIC1

Gene ID

1780

Swiss Prot

O14576

Accession Number

NP_004402

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DYNC1I1

Target

DYNC1I1 belongs to the dynein intermediate chain family. It contains 7 WD repeats. The intermediate chains seem to help dynein bind to dynactin 150 kDa component. DYNC1I1 may play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

Partner Proteins

AMBRA1; TRIM58; BECN1; DYNLL1; UBC; Bicd2; DYNC1LI1; DCTN2; DYNC1H1; DCTN1; Ccdc64b; Ccdc64; GNB1; KLC3; EMILIN1; TUBB3; PAFAH1B1; KCNA5; CUL3; KIAA0368; DNM2; CADM4; RUNDC3B; FAM110A; FAM83D; C2orf44; TAOK1; NAGK; KAT7; NUDT21; TK1; SMN1; RAP1GAP; PIN1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

73kDa

References & Citations

Pfister, K.K., (2005) J. Cell Biol. 171 (3), 411-413

Shipping Conditions

Wet Ice

Protein Length

645

NCBI Gene Symbol

DYNC1I1

NCBI GB Accession Number

DYNC1I1

Host or Source

Rabbit

Protein Name

Cytoplasmic dynein 1 intermediate chain 1

Nucleotide Accession Number

NM_004411

Peptide Sequence

IREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISP

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