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CSNK2A1 Antibody - middle region : Biotin (ARP51990_P050-Biotin)

Product Specifications

Gene Name

Casein kinase 2, alpha 1 polypeptide

Gene Aliases

CKII, Cka1, Cka2, CK2A1, OCNDS

Gene ID

1457

Swiss Prot

P68400

Accession Number

NP_001886

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CSNK2A1

Target

Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. CSNK2A1 represents the alpha subunit.Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.

Partner Proteins

MAGEA11; HDAC3; RNF111; NFYA; SGT1; STAC3; SUGT1; THAP1; AKT1; AURKA; CEP76; TP53; CEP57; RPS3; EGFR; UBC; POP1; WWOX; RNF2; rev; NAP1; EPB41L2; CALD1; HECW2; CDK11A; CAV2; CSNK2B; RNF11; NRF1; MYH9; IGSF8; ICAM1; HMGA1; HDAC1; GCH1; ACE; CSNK2A2; PRNP; D

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CSNK2A1 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Lehnert, S., (2008) Oncogene 27 (17), 2390-2400

Shipping Conditions

Wet Ice

Protein Length

391

NCBI Gene Symbol

CSNK2A1

NCBI GB Accession Number

CSNK2A1

Host or Source

Rabbit

Protein Name

Casein kinase II subunit alpha

Nucleotide Accession Number

NM_001895

Peptide Sequence

LGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDP

Subunit

Alpha

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