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EIF2B1 Antibody - C-terminal region : HRP (ARP51963_P050-HRP)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa

Gene Aliases

EIF2B, EIF2BA

Gene ID

1967

Swiss Prot

Q14232

Accession Number

NP_001405

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2B1

Target

EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM) .

Partner Proteins

RD3; WDYHV1; GORASP2; EIF2B1; UBC; GCD2; GCD6; EIF2B2; STK11; DCC; MRPL4; EIF2S2; EIF2S1; ARL4D; CREBBP; ADRB2; ADRA2B; ADRA2C; ADRA2A; EIF2B5; DCD; PDIA4; EIF2B3; HNRNPL; ARHGDIA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

EIF2B1 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 79%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Maletkovic, J., (2008) J. Child Neurol. 23 (2), 205-215

Shipping Conditions

Wet Ice

Protein Length

305

NCBI Gene Symbol

EIF2B1

NCBI GB Accession Number

EIF2B1

Host or Source

Rabbit

Protein Name

Translation initiation factor eIF-2B subunit alpha

Nucleotide Accession Number

NM_001414

Peptide Sequence

ADTLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKL

Subunit

Alpha

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