EIF2B1 Antibody - C-terminal region : Biotin (ARP51963_P050-Biotin)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa

Gene Aliases

EIF2B, EIF2BA

Gene ID

1967

Swiss Prot

Q14232

Accession Number

NP_001405

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2B1

Target

EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM) .

Partner Proteins

RD3; WDYHV1; GORASP2; EIF2B1; UBC; GCD2; GCD6; EIF2B2; STK11; DCC; MRPL4; EIF2S2; EIF2S1; ARL4D; CREBBP; ADRB2; ADRA2B; ADRA2C; ADRA2A; EIF2B5; DCD; PDIA4; EIF2B3; HNRNPL; ARHGDIA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

EIF2B1 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 79%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Maletkovic, J., (2008) J. Child Neurol. 23 (2), 205-215

Shipping Conditions

Wet Ice

Protein Length

305

NCBI Gene Symbol

EIF2B1

NCBI GB Accession Number

EIF2B1

Host or Source

Rabbit

Protein Name

Translation initiation factor eIF-2B subunit alpha

Nucleotide Accession Number

NM_001414

Peptide Sequence

ADTLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKL

Subunit

Alpha

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