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AP1G1 Antibody - C-terminal region : HRP (ARP51923_P050-HRP)

Product Specifications

Gene Name

Adaptor-related protein complex 1, gamma 1 subunit

Gene Aliases

ADTG, CLAPG1

Gene ID

164

Swiss Prot

O43747

Accession Number

NP_001119

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AP1G1

Target

Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. AP1G1 is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family.Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBL7; AP1S2; UBC; EGFR; GPRASP2; PASK; ASB10; PRRC1; OSBPL11; NPM3; TRIP10; KIF13A; ZNF512B; SYNRG; RABEP1; AP1M1; MAP1A; AP1S1; AP2M1; AP1B1; CLINT1; CLTC; gag; JUN; AP1AR; RABGEF1; AFTPH; DNER; AP1M2; AP1G1; SYP; SPTB; ARF1; AP2S1; NECAP2; NECAP1; RAB5A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

AP1G1 is supported by BioGPS gene expression data to be expressed in HepG2, Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

91kDa

References & Citations

Rost, M., (2006) J. Biol. Chem. 281 (39), 29297-29308

Shipping Conditions

Wet Ice

Protein Length

822

NCBI Gene Symbol

AP1G1

NCBI GB Accession Number

AP1G1

Host or Source

Rabbit

Protein Name

AP-1 complex subunit gamma-1

Nucleotide Accession Number

NM_001128

Peptide Sequence

DHMRSALLERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTS

Subunit

Gamma-1

Frequently Asked Questions

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