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AP1G1 Antibody - C-terminal region : Biotin (ARP51923_P050-Biotin)

Product Specifications

Gene Name

Adaptor-related protein complex 1, gamma 1 subunit

Gene Aliases

ADTG, CLAPG1

Gene ID

164

Swiss Prot

O43747

Accession Number

NP_001119

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AP1G1

Target

Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. AP1G1 is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family.Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBL7; AP1S2; UBC; EGFR; GPRASP2; PASK; ASB10; PRRC1; OSBPL11; NPM3; TRIP10; KIF13A; ZNF512B; SYNRG; RABEP1; AP1M1; MAP1A; AP1S1; AP2M1; AP1B1; CLINT1; CLTC; gag; JUN; AP1AR; RABGEF1; AFTPH; DNER; AP1M2; AP1G1; SYP; SPTB; ARF1; AP2S1; NECAP2; NECAP1; RAB5A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

AP1G1 is supported by BioGPS gene expression data to be expressed in HepG2, Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

91kDa

References & Citations

Rost, M., (2006) J. Biol. Chem. 281 (39), 29297-29308

Shipping Conditions

Wet Ice

Protein Length

822

NCBI Gene Symbol

AP1G1

NCBI GB Accession Number

AP1G1

Host or Source

Rabbit

Protein Name

AP-1 complex subunit gamma-1

Nucleotide Accession Number

NM_001128

Peptide Sequence

DHMRSALLERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTS

Subunit

Gamma-1

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