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SERPINA3 Antibody - middle region : Biotin (ARP51880_P050-Biotin)

Product Specifications

Gene Name

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

Gene Aliases

ACT, AACT, GIG24, GIG25

Gene ID

12

Swiss Prot

P01011

Accession Number

NP_001076

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SERPINA3

Target

SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease.The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ADH1B; ZNRD1; LAMC3; ABCC5; NFKB1; LMNB1; ATP6V1B1; PSMA3; DNAJC1; ADAMTS4; CTRC; POLA1; F5; KLK3; ERBB2; KLK2; HOXB1; MST1; ELANE; CELA1; MMP1; CMA1; CTRB1; CTRL; CTSG; SERPINA3; APP; LRP1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Zhao, Y., (2008) FEBS J. 275 (5), 1025-1038

Shipping Conditions

Wet Ice

Protein Length

423

NCBI Gene Symbol

SERPINA3

NCBI GB Accession Number

SERPINA3

Host or Source

Rabbit

Protein Name

Alpha-1-antichymotrypsin

Nucleotide Accession Number

NM_001085

Peptide Sequence

FRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSL

Frequently Asked Questions

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