CCT7 Antibody - middle region : Biotin (ARP51808_P050-Biotin)

Product Specifications

Gene Name

Chaperonin containing TCP1, subunit 7 (eta)

Gene Aliases

CCTH, CCTETA, NIP7-1, TCP1ETA

Gene ID

10574

Swiss Prot

Q99832

Accession Number

NP_006420

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CCT7

Target

CCT7 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.

Partner Proteins

SSSCA1; TP53; FUS; HUWE1; NEDD1; UBC; TUBG1; SUMO2; LGALS3BP; CDC20; MDM2; WWOX; ASB7; CCT3; CCT6A; PRPF40A; CCT5; CCT8; CCT2; CCT4; FBXO6; UBD; FBXW4; BAG3; HDAC6; HDAC3; ILK; CDK5; CDK2; AICDA; PAN2; METTL21B; VCAM1; FAM86B2; METTL18; PEX14; NOS2; NKX3-

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

CCT7 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 93%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.