AHCY Antibody - N-terminal region : Biotin (ARP51768_P050-Biotin)
Product Specifications
Gene Name
Adenosylhomocysteinase
Gene Aliases
SAHH, adoHcyase
Gene ID
191
Swiss Prot
P23526
Accession Number
NP_000678
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human AHCY
Target
S-adenosylhomocysteine hydrolase catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy) . Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.S-adenosylhomocysteine hydrolase catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy) . Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
ANKRD40; C1orf50; APPBP2; HUWE1; UBC; FUS; AHCY; SUMO2; SUMO3; SUMO1; NEDD8; ASB16; MSN; MC1R; HK1; HEXA; HDGF; FH; EEF1A2; DHX15; CAPZB; ATIC; ACAT2; H2AFV; NSFL1C; OGFOD1; PAPSS1; UBA3; TBCE; PYGL; HECW2; FBXO6; YWHAQ; gag-pol; PXN; DAB2; ATF2; TRAF3IP1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 86%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
References & Citations
Li, Q.S., (2008) Biochemistry 47 (17), 4983-4991
Shipping Conditions
Wet Ice
Protein Length
432
NCBI Gene Symbol
AHCY
NCBI GB Accession Number
AHCY
Host or Source
Rabbit
Protein Name
Adenosylhomocysteinase
Nucleotide Accession Number
NM_000687
Peptide Sequence
SDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIA
Frequently Asked Questions
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