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ADH5 Antibody - middle region : Biotin (ARP51767_P050-Biotin)

Selected Variant

ARP51767_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Alcohol dehydrogenase 5 (class III), chi polypeptide

Gene Aliases

FDH, ADHX, ADH-3, AMEDS, BMFS7, FALDH, GSNOR, GSH-FDH, HEL-S-60p

Gene ID

128

Swiss Prot

P11766

Accession Number

NP_000662

Host

Rabbit

Reactivity

Human, Mouse, Rat, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ADH5

Target

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Partner Proteins

UBC; HDAC1; SNTA1; ADH5; PQLC1; VTN; PRDX1; ESRRA; CSNK2B; ARNT; APP; TP63; TP73; TP53; CHD3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Horse: 79%; Human: 100%; Mouse: 93%; Pig: 79%; Rabbit: 83%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

Shipping Conditions

Wet Ice

Protein Length

374

NCBI Gene Symbol

ADH5

NCBI GB Accession Number

ADH5

Host or Source

Rabbit

Protein Name

Alcohol dehydrogenase class-3

Nucleotide Accession Number

NM_000671

Peptide Sequence

KSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVV

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