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INTS4 Antibody - middle region: Biotin (ARP51694_P050-Biotin)

Product Specifications

Gene Name

Integrator complex subunit 4

Gene Aliases

INT4, MST093

Gene ID

92105

Swiss Prot

Q96HW7

Accession Number

NP_291025

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human INTS4

Target

INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2) .INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]) .[supplied by OMIM].

Partner Proteins

USHBP1; ZMIZ2; HGS; UBC; HECW2; INTS9; UBD; SUMO2; INTS10; SHFM1; INTS5; INTS3; INTS6; INTS1; RPAP2; KIAA0513

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

108kDa

Shipping Conditions

Wet Ice

Protein Length

963

NCBI Gene Symbol

INTS4

Protein Name

Integrator complex subunit 4

Nucleotide Accession Number

NM_033547

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