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INTS4 Antibody - middle region : Biotin (ARP51694_P050-Biotin)

Product Specifications

Gene Name

Integrator complex subunit 4

Gene Aliases

INT4, MST093

Gene ID

92105

Swiss Prot

Q96HW7

Accession Number

NP_291025

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human INTS4

Target

INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2) .INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]) .[supplied by OMIM].

Partner Proteins

USHBP1; ZMIZ2; HGS; UBC; HECW2; INTS9; UBD; SUMO2; INTS10; SHFM1; INTS5; INTS3; INTS6; INTS1; RPAP2; KIAA0513

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

108kDa

References & Citations

Baillat, D., (2005) Cell 123 (2), 265-276

Shipping Conditions

Wet Ice

Protein Length

963

NCBI Gene Symbol

INTS4

NCBI GB Accession Number

INTS4

Host or Source

Rabbit

Protein Name

Integrator complex subunit 4

Nucleotide Accession Number

NM_033547

Peptide Sequence

PAEVVKILQTMLRQSAFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGL

Subunit

4

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