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PACS2 Antibody - middle region : FITC (ARP51659_P050-FITC)

Selected Variant

ARP51659_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Phosphofurin acidic cluster sorting protein 2

Gene Aliases

DEE66, EIEE66, PACS-2, PACS1L

Gene ID

23241

Swiss Prot

Q86VP3

Accession Number

NP_056012

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PACS2

Target

PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER) -mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Partner Proteins

UBC; TRAF2; BIRC3; BIRC2; PKD2; BID

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

98kDa

Shipping Conditions

Wet Ice

Protein Length

889

NCBI Gene Symbol

PACS2

NCBI GB Accession Number

PACS2

Host or Source

Rabbit

Protein Name

Phosphofurin acidic cluster sorting protein 2

Nucleotide Accession Number

NM_015197

Peptide Sequence

AHQLPIAEAMLTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDD

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