PACS2 Antibody - middle region: FITC (ARP51659_P050-FITC)
Product Specifications
Gene Name
Phosphofurin acidic cluster sorting protein 2
Gene Aliases
DEE66, EIEE66, PACS-2, PACS1L
Gene ID
23241
Swiss Prot
Q86VP3
Accession Number
NP_056012
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PACS2
Target
PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER) -mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Partner Proteins
UBC; TRAF2; BIRC3; BIRC2; PKD2; BID
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
98kDa
Shipping Conditions
Wet Ice
Protein Length
889
NCBI Gene Symbol
PACS2
Protein Name
Phosphofurin acidic cluster sorting protein 2
Nucleotide Accession Number
NM_015197
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