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PAXIP1 Antibody - N-terminal region : Biotin (ARP51642_P050-Biotin)

Selected Variant

ARP51642_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

PAX interacting (with transcription-activation domain) protein 1

Gene Aliases

PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L

Gene ID

22976

Swiss Prot

Q6ZW49

Accession Number

EAX04525

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1

Target

PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.

Partner Proteins

MAPRE2; POM121; NXT1; PPARG; XAGE1E; SMAD2; SPATA18; COMTD1; BTBD16; DIS3L; LACTB; HNRNPLL; ZNF251; ZNF622; BTBD6; C7orf50; FAM175A; TMEM120A; FAHD1; TM2D3; ATHL1; CENPU; DYNC2H1; BRCC3; KRI1; ANAPC1; NOM1; POLR1E; NCAPG; AASDHPPT; RBM25; CATSPERG; WDR48

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PAXIP1 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

Shipping Conditions

Wet Ice

Protein Length

697

NCBI Gene Symbol

PAXIP1

NCBI GB Accession Number

PAXIP1

Host or Source

Rabbit

Protein Name

PAX-interacting protein 1

Nucleotide Accession Number

NM_007349

Peptide Sequence

MFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVP

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