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HIST2H2AA3 Antibody - middle region : FITC (ARP51481_T100-FITC)

Product Specifications

Gene Name

Histone cluster 2, H2aa3

Gene Aliases

H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2AC19, H2a-615, HIST2H2AA, HIST2H2AA3

Gene ID

8337

Swiss Prot

Q7L7L0

Accession Number

NP_003507

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AA3

Target

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AA3 is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

USP21; DNAJC2; USP16; AURKB; UBC; WWOX; BAP1; SUZ12; RNF2; HCVgp1; PRMT6; IL33; APP; NOC2L; MEN1; SUMO2; RNF20; MSL2; BMI1; RNF168; HDAC1; PARP1; SRRM1; G3BP1; UBE2H; RCC1; TBL1X

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

14kDa

References & Citations

Gregory, S.G., (2006) Nature 441 (7091), 315-321

Shipping Conditions

Wet Ice

Protein Length

130

NCBI Gene Symbol

HIST2H2AA3

NCBI GB Accession Number

HIST2H2AA3

Host or Source

Rabbit

Protein Name

Histone H2A type 3

Nucleotide Accession Number

NM_003516

Peptide Sequence

PRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK

Frequently Asked Questions

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